PRF Injections in Newport Beach, CA
What is PRF?
PRF is the next generation of regenerative injectable therapy — everything PRP offers, with a more concentrated, longer-acting biological response.
PRF (Platelet-Rich Fibrin) is derived from your own blood — but processed without anticoagulants and at a lower centrifuge speed than standard PRP. This produces a fibrin matrix: a natural biological scaffold that holds platelets, white blood cells, and growth factors precisely at the treatment site. Instead of dispersing quickly like PRP, PRF releases its growth factors slowly over days — providing a sustained regenerative signal that drives deeper collagen production and more lasting skin improvement.
- 100% natural — derived entirely from your own blood, no additives
- Higher platelet and growth factor concentration than standard PRP
- Fibrin matrix delivers sustained growth factor release over days
- Stimulates collagen, elastin, and natural tissue repair
- Can be combined with microneedling, RF, or exosome therapy
Your Own Biology — Concentrated and Sustained
PRF injections at Grey Aesthetics deliver a richer, longer-lasting regenerative response than standard PRP — using nothing but your own blood to rebuild collagen, restore skin quality, and stimulate natural healing.
Benefits of PRF Injections
Sustained Growth Factor Release
PRF creates a fibrin matrix scaffold that traps platelets in place at the treatment site. This means growth factors are released slowly over days — not hours like standard PRP — delivering more prolonged biological stimulation.
No Anticoagulants — 100% Natural
PRF is processed without the anticoagulants used in standard PRP preparation. This preserves a richer concentration of platelets, white blood cells, and fibrin — all drawn entirely from your own blood.
Higher Platelet Concentration
PRF is spun at a lower centrifuge speed than PRP, which results in a higher concentration of platelets and growth factors. More growth factors mean a stronger biological signal for collagen production and tissue repair.
Versatile Applications
PRF can be used for facial skin rejuvenation, under-eye hollows, hair restoration, and as a complement to microneedling and other regenerative treatments — making it one of the most flexible regenerative injectables available.
What Conditions Can PRF Treat?
- Fine lines and wrinkles
- Under-eye hollows and dark circles
- Dull or uneven skin texture and tone
- Hair thinning and early-stage hair loss
- Acne scars and post-inflammatory changes
- Loss of skin elasticity and firmness
- Enhancing results from microneedling or RF treatments
- Natural rejuvenation without synthetic materials
Who is a Good Candidate for PRF Injections?
PRF is an excellent option for a wide range of patients seeking natural, advanced regenerative treatment. You may be an ideal candidate if you:
- Have fine lines, wrinkles, or early signs of facial aging
- Deal with acne scars, hyperpigmentation, or uneven skin texture
- Experience hair thinning or early-stage hair loss
- Want a natural, non-synthetic approach to skin or hair rejuvenation
- Are looking to enhance or extend results from microneedling or RF treatments
- Prefer the more potent, longer-acting option compared to standard PRP
Why Clients Choose Grey Aesthetics for PRF
- Experienced Medical Professionals: Our team specializes in regenerative aesthetics and has extensive experience with PRF preparation and delivery — ensuring safe, precise treatments with optimized platelet concentration.
- Both PRP and PRF Available: We offer both standard PRP and the more advanced PRF — and will recommend the best option for your specific goals at consultation. No pressure to choose the more expensive option unless it genuinely serves you better.
- Patient-Centered Care: We prioritize your comfort, safety, and satisfaction throughout every step — from the initial consultation through post-procedure follow-up and beyond.
- Powerful Treatment Combinations: PRF delivers amplified results when paired with microneedling, RF microneedling, or exosome therapy — all available at Grey Aesthetics for a complete regenerative protocol.
- Honest Guidance: We'll tell you honestly what PRF can and can't do for your specific concerns. If a different treatment would serve your goals better, we'll say so.
What Our Patients Are Saying
“Great medspa very tailored to individual need and leans toward natural treatments that work deep and stimulate our own collagen / healing response.”
— Alicia Jerome
“Beautiful and professional spa with pleasant staff that are also extremely educated and a gift to their profession. I see results in first treatment.”
— Lisa Fallon
“They were very personable and patient with my questions and curiosity. I was very comfortable. The end results were amazing. I would definitely recommend for smoother skin.”
— Katherine Simmons
Frequently Asked Questions
What is PRF and how is it different from PRP?
PRF (Platelet-Rich Fibrin) is an advanced form of PRP. Both are derived from your own blood, but PRF is processed without anticoagulants and at a lower centrifuge speed. This produces a fibrin matrix — a natural scaffold that holds platelets, white blood cells, and growth factors in place at the treatment site, allowing for a slower, more sustained release over days rather than hours. This extended release window produces a stronger and longer-lasting regenerative effect.
What conditions can PRF treat?
PRF is effective for skin rejuvenation including fine lines, uneven texture, dullness, and under-eye hollows. It is also used for hair thinning and early hair loss, acne scarring, and as a powerful add-on to microneedling or RF microneedling procedures. The sustained growth factor release makes it particularly effective for regenerative applications.
How many PRF sessions will I need?
Most patients start with a series of 2–3 sessions spaced 4–6 weeks apart to achieve optimal results. The exact number depends on your specific concerns and goals. Maintenance sessions once or twice a year can help sustain the improvements, particularly for hair restoration.
Is PRF painful? What is the downtime?
PRF injections are generally well-tolerated. Topical numbing cream is applied before treatment to minimize discomfort. After treatment, mild redness, swelling, or bruising at injection sites may occur — these typically resolve within 1–3 days. Most patients return to normal activities the same day.
Which is better — PRP or PRF?
PRF is generally considered the more advanced option. Its higher growth factor concentration, absence of anticoagulants, and fibrin matrix scaffold make it biologically richer and longer-acting than standard PRP. However, both are effective and your provider at Grey Aesthetics will recommend the best option based on your specific treatment goals at consultation.
Can PRF be combined with other treatments?
Yes — PRF delivers significantly enhanced results when combined with microneedling (as a 'Fibrin Facial'), RF microneedling, or exosome therapy. For hair restoration, PRF can be combined with Kerafactor or laser treatments for comprehensive results. Our team will design the most effective combination protocol for your goals.
Restore Your Skin With Advanced PRF Therapy
Schedule a PRF injection consultation at Grey Aesthetics in Newport Beach. Discover how your body's own fibrin-rich biology can drive deeper, longer-lasting skin rejuvenation.